Synonyms : | BMP-2B, DVR4 | ||||||||||||||||
Description : | Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein. | ||||||||||||||||
Catalog #: | 120-05 | ||||||||||||||||
Source : | HeLa cells | ||||||||||||||||
Stability : | The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted BMP-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles. | ||||||||||||||||
Purity : | Greater than 97% by SDS-PAGE gel and HPLC analyses. | ||||||||||||||||
Endotoxin Level : | Endotoxin level is less than 0.1 ng per μg (1EU/μg). | ||||||||||||||||
Biological Activity : | Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. | ||||||||||||||||
AA Sequence : | HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP SAISMLY LDEYDKVVLK NYQEMVVEGC GCR | ||||||||||||||||
PubMed Link : | BMP-4 | ||||||||||||||||
Country of Origin : | USA | ||||||||||||||||
| | ||||||||||||||||
|
| ||||||||||||||||
| |
相關產品
免責聲明
- 凡本網注明“來源:化工儀器網”的所有作品,均為浙江興旺寶明通網絡有限公司-化工儀器網合法擁有版權或有權使用的作品,未經本網授權不得轉載、摘編或利用其它方式使用上述作品。已經本網授權使用作品的,應在授權范圍內使用,并注明“來源:化工儀器網”。違反上述聲明者,本網將追究其相關法律責任。
- 本網轉載并注明自其他來源(非化工儀器網)的作品,目的在于傳遞更多信息,并不代表本網贊同其觀點和對其真實性負責,不承擔此類作品侵權行為的直接責任及連帶責任。其他媒體、網站或個人從本網轉載時,必須保留本網注明的作品第一來源,并自負版權等法律責任。
- 如涉及作品內容、版權等問題,請在作品發表之日起一周內與本網聯系,否則視為放棄相關權利。