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Palmitic acid

MCE 國(guó)際站：Palmitic acid

品牌：MedChemExpress (MCE)

CAS：57-10-3

純度：0.9976

貨號(hào)：HY-N0830

中文名稱：棕櫚酸

Synonyms：棕櫚酸

存儲(chǔ)條件：室溫保存

運(yùn)輸條件：美國(guó)大陸的室溫；其他地方可能有所不同。

產(chǎn)品活性：Palmitic acid 是一種常見(jiàn)于動(dòng)物和植物中的長(zhǎng)鏈飽和脂肪酸。Palmitic acid 可以誘導(dǎo)小鼠顆粒細(xì)胞中葡萄糖調(diào)節(jié)蛋白 78 (GRP78) 和 CCAAT/增強(qiáng)子結(jié)合蛋白同源蛋白 (CHOP) 的表達(dá)。棕櫚酸鈉可以用于建立細(xì)胞脂肪變性模型。

IC50 & Target：Microbial Metabolite Human Endogenous Metabolite

熱銷產(chǎn)品：5(6)-ROX  | DBCO-PEG4-Maleimide  | Palmitoylethanolamide  | Atomoxetine (hydrochloride)  | Lenacapavir  | Neurofascin, Human (HEK293, His)  | ALX-5407 (hydrochloride)  | SGC-AAK1-1  | VLX600  | Biotin-PEG2-azide

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

參考文獻(xiàn)：

[1]. Harada H, et al. Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga. Anticancer Res. 2002 Sep-Oct;22(5):2587-90.

[2]. Wen-Jin Ding, et al. Expression of Notch family is altered in non alcoholic fatty liver disease. Mol Med Rep. 2020 Sep;22(3):1702-1708.

[3]. Liaqat H, et al. Antioxidant Effect of Wheat Germ Extracts and Their Antilipidemic Effect in Palmitic Acid-Induced Steatosis in HepG2 and 3T3-L1 Cells. Foods. 2021 May 12;10(5):1061.

[4]. Jiang H, et al. Palmitic acid promotes endothelial progenitor cells apoptosis via p38 and JNK mitogen-activated protein kinase pathways. Atherosclerosis. 2010 May;210(1):71-7.

[5]. Ding WJ, et al. Expression of Notch family is altered in non alcoholic fatty liver disease. Mol Med Rep. 2020 Sep;22(3):1702-1708. 

[6]. Urso CJ, et al. Palmitic Acid Lipotoxicity in Microglia Cells Is Ameliorated by Unsaturated Fatty Acids. Int J Mol Sci. 2021 Aug 23;22(16):9093. 

[7]. Wu D, et al. Palmitic acid exerts pro-inflammatory effects on vascular smooth muscle cells by inducing the expression of C-reactive protein, inducible nitric oxide synthase and tumor necrosis factor-α. Int J Mol Med. 2014 Dec;34(6):1706-12.