UA011170 Thrombopoietin R/TPO R His Tag Protein, Mouse
- 公司名稱 杭州斯達(dá)特生物科技有限公司
- 品牌 Starter/斯達(dá)特
- 型號 UA011170
- 產(chǎn)地 江蘇 南京
- 廠商性質(zhì) 生產(chǎn)廠家
- 更新時(shí)間 2025/7/3 21:53:37
- 訪問次數(shù) 37
聯(lián)系方式:王修明13774214275 查看聯(lián)系方式
聯(lián)系我們時(shí)請說明是化工儀器網(wǎng)上看到的信息,謝謝!
Thrombopoietin receptor (TPO-R), also known as TPO-R, is predominantly expressed on the surface of megakaryocytes (MKs), platelets, hemangioblasts, and hematopoietic stem cells (HSCs). Binding of thrombopoietin (TPO) to the megakaryocyte TPO-R leads to several effects: prevention of megakaryocyte apoptosis, increased megakaryocyte number, size, and ploidy, accelerated maturation of megakaryocytes, and internalization of the TPO/TPO-R complex. Thrombopoietin R is involved in multiple signal transduction pathways, including JAK, STAT, and MAP kinase pathways.