UA040075 FGF-21 Protein, Human
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- 公司名稱 杭州斯達特生物科技有限公司
- 品牌 Starter/斯達特
- 型號 UA040075
- 產(chǎn)地 江蘇 南京
- 廠商性質(zhì) 生產(chǎn)廠家
- 更新時間 2025/7/16 8:00:53
- 訪問次數(shù) 41
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Fibroblast Growth Factor 21（FGF-21） is a member of the fibroblast growth factor （FGF） family and it is involved in the modulation of cell proliferation, growth, and differentiation as well as cell metabolism. This protein is a secreted endocrine factor that functions as a major metabolic regulator, and stimulates the uptake of glucose in adipose tissue. FGF21 binds to FGFR1c complexed with β-Klotho expressed in adipocytes to activate the canonical FGF signaling pathway （ERK1/2） and the AMPK/PGC1α pathway. Therefore, FGF-21 is being pursued as a therapeutic target for diabetes and obesity.
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