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Wnt16抗原,信號通路Wnt16抗原

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  • 上傳時間

    2024年11月10日
關鍵詞
Wnt16,Wnt16抗體,信號通路Wnt16,信號通路Wnt16抗體 ,重組蛋白
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上海允麥生物科技有限公司
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資料簡介

Recombinant human Wnt16   

Protein Wnt 16 precursor; Protein Wnt-16; Wingless type MMTV integration site family member 16; WNT16; WNT16_HUMAN.    

濃度:1mg/ ml

來源:Recombinant Human

純度:95% SDS-PAGE

表達系統:Escherichia coli

標簽:His tag   

蛋白長度:Full length protein

內毒素水平:<1.000 Eu/µg

純化方法:HPLC

應用:SDS-PAGEWestern blotELISA

Biological activity,immunology research

保存:-20

保質期:1

The Wnt genes encode a family of secreted extracellular signaling glycoproteins, which function in a variety of important developmental processes such as regulation of cell growth and differentiation. Wnt proteins also play roles in carcinogenesis. Wnt-14, rather than Wnt-15, is preferentially expressed in various types of human cancer. Wnt-15 is expressed in fetal and adult kidney and is most homologous to Wnt-14. Wnt-16, another member in the Wnt family, has two mRNA isoforms, Wnt-16a and Wnt-16b. These isoforms differ in the composition of their 5'UTR and first exon, which results in differential expression. Wnt-16a is expressed only in pancreas, whereas Wnt-16b is highly expressed in adult kidney, placenta, brain, heart and spleen, but not in bone marrow. However, Wnt-16 transcripts are present in bone marrow and cell lines derived from pre-B acute lymphoblastoid leukemia patients carrying the E2A-Pbx1 hybrid gene. Thus, Wnt-16 is a downstream target of E2A-Pbx1, and the Wnt-16-mediated autocrine growth mechanism may contribute to the development of t(1;19) pre-B acute lymphoblastoid leukemias.



產品名稱:Rabbit Anti-Wnt16 antibody

Rabbit Anti-Wnt16 

別名:Protein Wnt 16 precursor; Protein Wnt-16; Wingless type MMTV integration site family member 16; WNT16; WNT16_HUMAN.               

來源:Rabbit

克隆類型:Polyclonal

濃度:1mg/ml

亞型:IgG

反應:Human (predicted: Mouse,Rat,Rabbit,Pig,Cow)

應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

理論分子量:37kDa

免疫原:KLH conjugated synthetic peptide derived from human Wnt16

保存:-20
保質期:1

 

 

產品名稱:Anti-Wnt16 antibody

Mouse Anti-Wnt16

別名:Protein Wnt 16 precursor; Protein Wnt-16; Wingless type MMTV integration site family member 16; WNT16; WNT16_HUMAN.                

來源:Mouse

克隆類型:Monoclonal

濃度:1mg/ml

亞型:IgG

反應:Human

應用:WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應:  Human

理論分子量:37kDa

免疫原:KLH conjugated synthetic peptide derived from human Wnt16

保存:-20
保質期:1

The Wnt genes encode a family of secreted extracellular signaling glycoproteins, which function in a variety of important developmental processes such as regulation of cell growth and differentiation. Wnt proteins also play roles in carcinogenesis. Wnt-14, rather than Wnt-15, is preferentially expressed in various types of human cancer. Wnt-15 is expressed in fetal and adult kidney and is most homologous to Wnt-14. Wnt-16, another member in the Wnt family, has two mRNA isoforms, Wnt-16a and Wnt-16b. These isoforms differ in the composition of their 5'UTR and first exon, which results in differential expression. Wnt-16a is expressed only in pancreas, whereas Wnt-16b is highly expressed in adult kidney, placenta, brain, heart and spleen, but not in bone marrow. However, Wnt-16 transcripts are present in bone marrow and cell lines derived from pre-B acute lymphoblastoid leukemia patients carrying the E2A-Pbx1 hybrid gene. Thus, Wnt-16 is a downstream target of E2A-Pbx1, and the Wnt-16-mediated autocrine growth mechanism may contribute to the development of t(1;19) pre-B acute lymphoblastoid leukemias.


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