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商品信息

產(chǎn)品英文名稱	Anti-GAPDH Rabbit Polyclonal Antibody
產(chǎn)品中文名稱	GAPDH兔多克隆抗體
別名	GAPDH; GAPD; CDABP0047; OK/SW-cl.12; Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; Peptidyl-cysteine S-nitrosylase GAPDH

商品屬性

克隆類型	多克隆
檢測類型	WB,IHC-P
反應(yīng)性	人,小鼠,雞,兔,猴,大鼠,綿羊
宿主	兔
濃度	1 mg/ml
免疫原	重組蛋白
產(chǎn)品形式	液體形式
基因ID	2597
目標(biāo)條帶分子量	37
蛋白序列鏈接	/uniprot/P04406
存儲緩沖液	PBS緩沖液（pH 7.4），含有0.5%BSA（穩(wěn)定劑），0.02％（防腐劑）和50％甘油。
保存建議	自發(fā)貨之日起，-20°C可穩(wěn)定保存1年。為限度的避免損失，請在打開管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。
運(yùn)輸條件	冰袋運(yùn)輸（藍(lán)冰）
警告	本文列出的產(chǎn)品僅供研究使用，不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用，不是建議使用我們的產(chǎn)品去違反任何或許可證。對于使用本產(chǎn)品可能發(fā)生的侵權(quán)或其他違規(guī)行為，我們不承擔(dān)任何責(zé)任。
其他	該抗體可檢測內(nèi)源蛋白

附加信息

背景

GAPDH encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. Glyceraldehyde-3-phosphate dehydrogenase has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of GAPDH catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). Glyceraldehyde-3-phosphate dehydrogenase has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, Glyceraldehyde-3-phosphate dehydrogenase contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.

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