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Deoxycholic acid

CAS No. : 83-44-3

產品活性：Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5.

研究領域：GPCR/G Protein  |  Metabolic Enzyme/Protease

作用靶點：G protein-coupled Bile Acid Receptor 1  |  Endogenous Metabolite

結構分類：甾體類

In Vitro: Deoxycholic acid (DCA) (100 μM) induces the production of gastric cancer cell line MGC803 resistant to acidified bile acids and enhances their survival and proliferation activity under bile acid stress.
Deoxycholic acid (DCA) (100 μM)-induced resistant cells shows altered morphology, significantly elevated telomerase activity, better cell viability and reduces apoptosis compared to normal MGC803 cells.

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