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產品簡介
xona 神經元突觸細胞微灌流系統的基底材料的拓撲形貌是影響細胞行為的重要因素之一,細胞與微納米結構圖案表面相互作用研究在細胞生物學、再生醫學和組織工程領域具有重要的意義。材料表面微納米圖案化不但可以提供結構模版,用以研究細胞對生長環境的響應特性,而且可以為組織再生用支架和植入性器件的設計提供基礎數據。
詳細介紹
Description of Neuron Device in DetailNat Methods. 2005 Aug;2(8):599-605.A microfluidic culture platform for CNS axonal injury, regeneration and transport.Taylor AM, Blurton-Jones M, Rhee SW, Cribbs DH, Cotman CW, Jeon NL.100umNeuronThe Neuron Device offered by Xona Microfluidics LLC is fabricated out of optically transparent and biologically inert Polydimethylsiloxane (PDMS). The Neuron Device consists of two chambers connected by microgrooves.The neuron device also makes it possible for the researcher to fluidically isolate cell bodies from axons. The device consists of two chambers connected by a much smaller microgroove barrier. The hydrostatic pressure between the two chambers separated by the microgrooves allows the researcher to fluidically isolate each chamber. This is accomplished by keeping the volumes in the wells on one side of the device higher than the other side of the device. The difference in volume creates hydrostatic pressure thus fluidically isolating each compartment.The total volume of the device is about 600 ul thus the researcher uses less of the expensive reagents typically used in neuronal culture.The neuron device also makes it possible to perform axotomy, cutting axons via vacuum aspiration in the distal chamber and observing their regrowth.xona microfluidics llc snd150 神經元突觸細胞微灌流系統xona microfluidics llc snd450 神經元突觸細胞微灌流系統xona microfluidics llc snd900 神經元突觸細胞微灌流系統xona microfluidics llc TCND500 神經元突觸細胞微灌流系統xona microfluidics llc TCND1000 神經元突觸細胞微灌流系統xona microfluidics llc RD150 神經元突觸細胞微灌流系統xona microfluidics llc RD450 神經元突觸細胞微灌流系統xona microfluidics llc RD900 神經元突觸細胞微灌流系統xona microfluidics llc ULP 神經元突觸細胞微灌流系統