僅用于工業(yè)應(yīng)用或科學研究，不可用于人類或動物的臨床診斷或治療，非藥用. Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-agent coupling （ADC） with antitumor activity