 | 培安有限公司 |
010-65528800
高 （市場部）
- 電話：
- 010-65528800
- 手機：
- 售后電話：
- 010-64278205
- 傳真：
- 010-65519722
- 聯系我時，
- 告知來自化工儀器網
- 個性化：
- www.pynnco.net
- 公司網站：
- http://www.pynnco.com
CEM微波合成用于ACP 65 的合成
閱讀：2010發布時間：2012-6-28
INTRODUCTION
The application of microwave energy has proved to be a major enabling tool for many chemical reactions requiring energy input, and recently microwave irradiation has been applied to solid phase peptide synthesis. Peptide synthesis often suffers from long reaction times and low yields due to problems such as aggregation. Microwave energy can help break up these aggregates improving the synthesis quality while speeding up the synthesis rate. The acyl carrier protein （ACP） fragment 65‐74, H‐Val‐Gln‐Ala‐Ala‐Ile‐Asp‐Tyr‐Ile‐Asn‐Gly‐OH, is a widely used standard model for demonstrating peptide synthesis efficiency. The presence of several hydrophobic residues, and in particular the hindered Val and Ile residues, can lead to poor coupling and deprotection reactions resulting in low yield and purity of the peptide.
In this application note ACP 65‐74 is synthesized in good yield and purity using microwave irradiation for the deprotection, coupling, and final cleavage steps.
更多詳情，請培安公司：
：北京： 上海： 成都： 廣州：
: sales@pynnco.com ：www.pynnco.com
以上信息由企業自行提供，信息內容的真實性、準確性和合法性由相關企業負責，化工儀器網對此不承擔任何保證責任。 溫馨提示：為規避購買風險，建議您在購買產品前務必確認供應商資質及產品質量。
