18906011628
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| Synonyms | Casein kinase II subunit alpha, EC 2.7.11.1, CK II, CK2-alpha, CK2?. |
| Introduction | The Casein kinase 2 （EC2.7.11.1） is a serine/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase 2. |
| Description | Casein Kinase 2 alpha Zea Mays Recombinant is a non-glycosylated polypeptide having a molecular mass of 39.2 kDa. Casein Kinase 2 is purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Formulation | CK2a is supplied in 50% glycerol. |
| Unit Definition | No protease activity detectable, specific activity > 1U/mg （1U = 1μmol/min at 37 degree C） using the synthetic peptide RRRDDDSDDD. |
| Storage Conditions | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity | Greater than 99% as determined by SDS-PAGE. |
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
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