色素上皮衍生因子（PEDF）是一種多能神經營養因子，在中樞神經系統和視網膜中均具有很強的活性。到目前為止，PEDF是在哺乳動物的眼腔中所發現的zui強的抗血管生長因子。有趣的是，zui近的研究顯示眼部PEDF水平的降低與糖尿病視網膜病變和其他神經視網膜營養不良性疾病存在相關性。并且，PEDF表現出來的神經營養特性和抗血管生成的特性，提示這種蛋白在控制與腫瘤生長相關的新血管生成中具有潛在的治療價值。為了便于研究這一重要的絲氨酸蛋白酶抑制蛋白超家族的成員-PEDF，我們研發了一種敏感的PEDF ELISA試劑盒，這種試劑盒通過使用多克隆抗體特異性的檢測存在于人的玻璃體和其他組織中的天然PEDF蛋白。與其他的商業性的PEDF ELISA試劑盒相比較，我們的PEDF ELISA試劑盒的敏感性幾乎是其他同類產品的50倍。事實上，我們的研究起初即以接近于其他PEDF ELISA試劑盒產品檢測限的PEDF濃度進行實驗的。如果您的研究需要對PEDF進行定量，我們的PEDF ELISA試劑盒將會是您的*選擇對象。

主要特點：
檢測限....范圍…..敏感性是同類產品的50倍

保存和操作：
保存在4 ºC，不要冷凍保存。產品自發貨日期起至少可以穩定保存6個月。

PEDF ELISA Kits
96-Well Microplate Assay
Pigment epithelium-derived factor （PEDF） is a multipotent neurotrophic factor with potent activity both in the central nervous system and in the retina. To date, PEDF is the most potent angiogenic inhibitor found in the mammalian ocular compartment. Interestingly, recent studies have shown that decreased ocular levels of PEDF are associated with diabetic retinopathy and other neuroretinal dystrophic diseases. In addition, the neurotropic and anti-angiogenic properties of PEDF suggest this protein is of potential therapeutic value for control of neovascularization associated with tumor growth.   To facilitate research on this important member of the serpin protein superfamily, we have developed a sensitive PEDF ELISA using polyclonal antibodies that specifically detects native PEDF protein in human vitreous and other tissues.   Compared to other commercially-available PEDF ELISA kits, our PEDF ELISA is nearly 50-times more sensitive than the competitor's product. In fact, our assay starts at PEDF concentrations that are near the limit-of-detection for other PEDF ELISAs （see above）.  If you need to quantify PEDF levels in your studies, our PEDF ELISA kit is the best solution to consider!
KIT FEATURES:
Limits of detection... range... 50X better than competitors' assay.
STORAGE & HANDLING:  
Store at 4ºC.  DO NOT FREEZE. Product is stable for at least six months from date of shipment.