9min快速濕轉儀，10min蛋白染色儀，全自動WB系統，預制膠，WB試劑，Protein A/Ni-NTA/Glutathione/Anti-His/Anti-flag Resin，磁珠，ECL發光試劑，血清，細胞，培養基，凋亡檢測試劑盒，細胞活力or增殖檢測試劑盒，細胞熒光染料，抗體，ELISA試劑盒，重組蛋白，真正無毒核酸染料，瓊脂糖，qPCR Mix，RT-PCR mix，質粒，外泌體解決方案，CRISPR/Cas9試劑等
| 供貨周期 | 一周 | 規格 | 1 Kit |
|---|---|---|---|
| 貨號 | L00338 | 應用領域 | 醫療衛生,環保,食品/農產品,生物產業,制藥/生物制藥 |
| 主要用途 | GenScript ToxinEraser™是一種高效的內毒素去除樹脂 |
GenScript ToxinEraser™ is an endototoxin removal resin of high efficiency. It is based on the affinity matrix of modified polymyxin B (PMB), which allows highly efficient endotoxin removal. The final endotoxin level can be decreased to less than 0.1 EU/ml with repeat use of ToxinEraser™ endotoxin removal resin. Final removal efficiency may vary depending on the sample type/source.
產品概述
Product Description：
Lipopolysaccharide (LPS) is a bacterial endotoxin, and a major constituent of the cell walls of gram- negative bacteria. During gram-negative bacteremia or endotoxemia, LPS is the principal pathophysiological mediator by which bacteria can cause hypotension, organ failure, disseminated intravascular coagulation, and fatal shock in mammalian hosts. Removal of endotoxin from drugs, injectables, and other biological products is necessary but can also be very difficult.
GenScript’s ToxinEraser™ is an endototoxin removal resin of high efficiency. It is based on affinity matrix of modified polymyxin B (PMB), which allows highly efficient endotoxin removal. The final endotoxin level can be decreased to less than 0.1 EU/ml with repeated use of ToxinEraser™ endotoxin removal resin. Final removal efficiency may vary depending on the sample type/source.
Key Features
High stability and high removal efficiency
High binding capacity: > 2, 000, 000 EU / ml (CV)
Fast flow without any constant speed pump
Reusable up to five times if properly regenerated
Ready-to-use reagents and materials, such as equilibration buffer, collection tubes, etc.
產品簡介
Product Information：Characteristics of ToxinEraser™ Endotoxin Removal Resin
Size：1.5 ml in pre-packed column
Binding Capacity：Up to 2,000,000 EU/ml resin
Ligand：Modified PMB (Polymixin B)
pH Stability：pH 5 -10
Support Matrix：4% cross-linked agarose, spherical beads
Mean Particle Size：90 μm
Storage：2°C to 8°C (Do not freeze.)
Equilibration Buffer：Phosphate-Buffer, pH 8.0
Regeneration Buffer：Sodium Phosphate-Buffer, pH 8.0; Triton-114
Types of substances that can be applied to the column：Purified recombinant proteins, peptides, antibodies, polysaccharides, etc.
Tolerable Ionic Strength：0.1 to 0.5 M NaCl
Tested reagents that do not interfere with performance：20% DMSO, 20% ethanol, 20% glycerol;1 M urea, 300 mM imidazole; 0.05% Tween 20, 10 mM DTT.
Storage
Regeneration and storage of the Column.
To regenerate the column, wash the column with 10 ml of equilibration buffer and allow the column to drain completely. Add ethanol to the regeneration buffer to a final concentration of 20%, adding at least 1.5 ml to the column for storage. Store at 2-8°C. Do not freeze.
Kit Contents
Kit Contents （Cat. No.:L00338）：PK
ToxinEraser™ Endotoxin Removal Resin：1.5 ml pre-packed column
Regeneration Buffer：125 ml
Equilibration Buffer：125 ml
Flow-Speed Control：1
Collection Tubes：1 bag (3 Tubes)
Tips (1 ml)：2 bags (6 Tips/bag)
Protocol：1
For research and manufacturing use. Direct human use, including taking orally and injection are forbidden.
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