Bub1 rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 更新時間 2025/7/3 8:43:45
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Source
Rabbit
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Applications
WB,ELISA
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Reactivity
Human
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Dilution
WB: 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
BUB1 Polyclonal Antibody detects endogenous levels of BUB1 protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human BUB1. AA range:781-830
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Uniprot No
O43683
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Alternative names
BUB1; BUB1L; Mitotic checkpoint serine/threonine-protein kinase BUB1; hBUB1; BUB1A
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
BUB1 mitotic checkpoint serine/threonine kinase(BUB1) Homo sapiens This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
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Other
BUB1, Mitotic checkpoint serine/threonine-protein kinase BUB1
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Mol.Wt (Da)
122375
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Concentration
1 mg/ml
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