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Bmx rabbit pAb2
- 公司名稱 上海貝博生物科技有限公司
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Source
Rabbit
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Applications
WB,IHC,IF,ELISA
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Reactivity
Human,Mouse
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Dilution
WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
Phospho-Bmx (Y40) Polyclonal Antibody detects endogenous levels of Bmx protein only when phosphorylated at Y40.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human ETK around the phosphorylation site of Tyr40. AA range:6-55
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Uniprot No
P51813
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Alternative names
BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
BMX non-receptor tyrosine kinase(BMX) Homo sapiens This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],
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Other
BMX, Cytoplasmic tyrosine-protein kinase BMX; Epithelial and endothelial tyrosine kinase; ETK; NTK38
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Mol.Wt (Da)
78011
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Concentration
1 mg/ml
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