BMPR-IB rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 更新時間 2025/7/2 21:40:15
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Source
Rabbit
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Applications
IHC,ELISA
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Reactivity
Human,Mouse
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Dilution
IHC 1:50-200, ELISA 1:10000-20000
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Storage
-20°C/1 year
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Specificity
The antibody detects endogenous BMPR-IB
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
Synthetic peptide from human protein at AA range: 21-70
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Uniprot No
O00238
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Alternative names
Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
bone morphogenetic protein receptor type 1B(BMPR1B) Homo sapiens This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligａnd binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for thi
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Other
BMPR1B, Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)
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Concentration
1 mg/ml
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