AT2B4 rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 更新時間 2025/7/15 10:18:28
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Source
Rabbit
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Applications
WB
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Reactivity
Human,Rat
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Dilution
WB 1：500-2000
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Storage
-20°C/1 year
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Specificity
This antibody detects endogenous levels of AT2B4 at Human/Rat
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Source/Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
Synthesized peptide derived from human AT2B4
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Uniprot No
P23634
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
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Other
ATP2B4 ATP2B2 MXRA1, AT2B4
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Mol.Wt (Da)
136510
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Concentration
1 mg/ml
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