BLNK (phospho Tyr84) rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 廠商性質 生產廠家
- 更新時間 2025/7/15 9:48:14
- 訪問次數 36
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Source
Rabbit
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Applications
WB,IHC,ELISA
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Reactivity
Human,Mouse,Rat
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Dilution
WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
Phospho-BLNK (Y84) Polyclonal Antibody detects endogenous levels of BLNK protein only when phosphorylated at Y84.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human BLNK around the phosphorylation site of Tyr84. AA range:50-99
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Uniprot No
Q8WV28
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Alternative names
BLNK; BASH; SLP65; B-cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa;
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
B-cell linker(BLNK) Homo sapiens This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012],
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Other
BLNK, B-cell linker protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa;
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Mol.Wt (Da)
50466
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Concentration
1 mg/ml
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