BinCARD rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 更新時間 2025/7/15 9:26:52
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Source
Rabbit
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Applications
IHC,ELISA
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Reactivity
Human,Mouse
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Dilution
IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
BinCARD Polyclonal Antibody detects endogenous levels of BinCARD protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human C9orf89. AA range:21-70
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Uniprot No
Q96LW7
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Alternative names
C9orf89; Bcl10-interacting CARD protein; BinCARD
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.,PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CARD domain.,subcellular location:Co-expression with BCL10 induced translocation from nucleus to cytosol.,subunit:Associates with BCL10 by CARD-CARD interaction.,tissue specificity:Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.,
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Other
C9orf89, Bcl10-interacting CARD protein
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Mol.Wt (Da)
25589
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Concentration
1 mg/ml
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