Blk (phospho Tyr501) rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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Source
Rabbit
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Applications
IHC,ELISA
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Reactivity
Human,Mouse,Rat
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Dilution
IHC: 1:100 - 1:300. ELISA: 1:20000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
Phospho-Blk (Y501) Polyclonal Antibody detects endogenous levels of Blk protein only when phosphorylated at Y501.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human BLK around the phosphorylation site of Tyr501. AA range:456-505
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Uniprot No
P51451
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Alternative names
BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
BLK proto-oncogene, Src family tyrosine kinase(BLK) Homo sapiens This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],
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Other
BLK, Tyrosine-protein kinase Blk
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Mol.Wt (Da)
57706
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Concentration
1 mg/ml
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