Bradykinin B1 R rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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Source
Rabbit
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Applications
WB,IF,ELISA
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Reactivity
Human
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Dilution
WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250
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Uniprot No
P46663
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Alternative names
BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
bradykinin receptor B1(BDKRB1) Homo sapiens Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
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Other
BDKRB1, B1 bradykinin receptor
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Mol.Wt (Da)
40495
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Concentration
1 mg/ml
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