Bmi-1 Rabbit rabbit pAb(F270)
- 公司名稱 上海貝博生物科技有限公司
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Source
Rabbit
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Applications
WB
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Reactivity
Human
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Dilution
WB 1:500-2000
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Storage
-20°C/1 year
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Specificity
This antibody detects endogenous levels of human Bmi-1
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Source/Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
Recombinant Protein derived from human Bmi-1
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Uniprot No
P35226
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Alternative names
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],
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Other
BMI1 PCGF4 RNF51, Bmi-1
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Concentration
1 mg/ml
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