AR-α1B rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 更新時間 2025/7/14 21:32:05
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Source
Rabbit
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Applications
WB,IF,ELISA
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Reactivity
Human,Mouse,Rat
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Dilution
WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
AR-α1B Polyclonal Antibody detects endogenous levels of AR-α1B protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human ADRA1B. AA range:431-480
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Uniprot No
P35368
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Alternative names
ADRA1B; Alpha-1B adrenergic receptor; Alpha-1B adrenoreceptor; Alpha-1B adrenoceptor
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
adrenoceptor alpha 1B(ADRA1B) Homo sapiens Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008],
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Other
ADRA1B, Alpha-1B adrenergic receptor
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Mol.Wt (Da)
56836
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Concentration
1 mg/ml
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