Artn rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 更新時間 2025/7/14 19:06:36
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Source
Rabbit
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Applications
IHC,ELISA
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Reactivity
Human
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Dilution
IHC 1:50-200, ELISA 1:10000-20000
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Storage
-20°C/1 year
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Specificity
The antibody detects endogenous Artn
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
Synthetic peptide from human protein at AA range: 101-150
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Uniprot No
Q5T4W7
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Alternative names
Artemin (Enovin) (Neublastin)
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
artemin(ARTN) Homo sapiens This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. [provided by RefSeq, Aug 2016],
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Other
ARTN EVN, Artemin (Enovin) (Neublastin)
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Concentration
1 mg/ml
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