ARVC rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 更新時間 2025/7/14 19:04:34
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Source
Rabbit
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Applications
WB
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Reactivity
Human, Mouse
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Dilution
WB 1:500-2000
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Storage
-20°C/1 year
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Specificity
This antibody detects endogenous levels of ARVC at Human/Mouse
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Source/Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
Synthesized peptide derived from human ARVC
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Uniprot No
O00192
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Alternative names
Armadillo repeat protein deleted in velo-cardio-facial syndrome
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.257% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein. [provided by RefSeq, Jun 2010],
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Other
ARVCF, ARVC, Armadillo repeat protein deleted in velo-cardio-facial syndrome
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Concentration
1 mg/ml
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