ARRS rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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Source
Rabbit
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Applications
WB,ELISA
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Reactivity
Human
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Dilution
WB 1:500-2000 ELISA 1:5000-20000
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Storage
-20°C/1 year
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Specificity
ARRS Polyclonal Antibody detects endogenous levels of protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
Synthesized peptide derived from human protein . at AA range: 210-290
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Uniprot No
P10523
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Form
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
S-antigen visual arrestin(SAG) Homo sapiens Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal glａnd and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008],
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Other
SAG, S-arrestin (48 kDa protein) (Retinal S-antigen) (S-AG) (Rod photoreceptor arrestin)
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Concentration
1 mg/ml
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