AT7L3 rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 廠商性質 生產廠家
- 更新時間 2025/7/14 18:05:11
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Source
Rabbit
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Applications
WB,ELISA
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Reactivity
Human,Mouse
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Dilution
WB 1:500-2000 ELISA 1:5000-20000
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Storage
-20°C/1 year
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Specificity
AT7L3 Polyclonal Antibody detects endogenous levels of protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
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Uniprot No
Q14CW9
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Form
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
domain:The SGF11-type zinc finger mediates the interaction with USP22 and ENY2.,function:Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.,similarity:Belongs to the SGF11 family.,similarity:Contains 1 SCA7 domain.,similarity:Contains 1 SGF11-type zinc finger.,subunit:Component of some SAGA transcription coactivator-HAT complex, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ATXN7L3, ENY2 and USP22 form a subcomplex required for histone deubiquitinylation. Interacts directly with ENY2 and USP22.,
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Other
ATXN7L3, Ataxin-7-like protein 3 (SAGA-associated factor 11 homolog)
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Concentration
1 mg/ml
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