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ATP7A rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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Source
Rabbit
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Applications
IHC,ELISA
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Reactivity
Human,Mouse,Rat
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Dilution
IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
ATP7A Polyclonal Antibody detects endogenous levels of ATP7A protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human ATP7A. AA range:591-640
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Uniprot No
Q04656
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Alternative names
ATP7A; MC1; MNK; Copper-transporting ATPase 1; Copper pump 1; Menkes disease-associated protein
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
ATPase copper transporting alpha(ATP7A) Homo sapiens This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. [provided by RefSeq, Aug 2013],
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Other
ATP7A, Copper-transporting ATPase 1
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Mol.Wt (Da)
163335/165110/172078/154357
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Concentration
1 mg/ml
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