BBS7 rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 更新時間 2025/7/2 11:02:44
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Source
Rabbit
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Applications
WB
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Reactivity
Human, Mouse
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Dilution
WB 1：500-2000
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Storage
-20°C/1 year
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Specificity
This antibody detects endogenous levels of BBS7 at Human/Mouse
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Source/Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
Synthesized peptide derived from human BBS7
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Uniprot No
Q8IWZ6
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy; however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014],
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Other
BBS7 BBS2L1, BBS7
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Mol.Wt (Da)
78650
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Concentration
1 mg/ml
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