BAP1 rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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Source
Rabbit
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Applications
WB,ELISA
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Reactivity
Human,Rat,Mouse
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Dilution
WB 1:500-2000 ELISA 1:5000-20000
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Storage
-20°C/1 year
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Specificity
BAP1 Polyclonal Antibody detects endogenous levels of protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
Synthesized peptide derived from human protein . at AA range: 150-230
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Uniprot No
Q92560
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Form
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
BRCA1 associated protein 1(BAP1) Homo sapiens This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013],
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Other
BAP1 KIAA0272 hucep-6, Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Cerebral protein 6)
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Concentration
1 mg/ml
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