ASC-1 rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 廠商性質 生產廠家
- 更新時間 2025/7/14 12:58:38
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Source
Rabbit
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Applications
WB,IHC,IF,ELISA
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Reactivity
Human,Mouse
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Dilution
WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
ASC-1 Polyclonal Antibody detects endogenous levels of ASC-1 protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human TRIP4. AA range:81-130
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Uniprot No
Q15650
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Alternative names
TRIP4; Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
thyroid hormone receptor interactor 4(TRIP4) Homo sapiens This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1). [provided by RefSeq, Apr 2016],
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Other
TRIP4, Activating signal cointegrator 1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4
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Mol.Wt (Da)
66146
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Concentration
1 mg/ml
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