ATR (phospho Ser428) rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
- 品牌
- 型號
- 產地
- 廠商性質 生產廠家
- 更新時間 2025/7/14 8:31:29
- 訪問次數 31
聯系方式：張經理18930271235 查看聯系方式
聯系我們時請說明是化工儀器網上看到的信息，謝謝!
-
Source
Rabbit
-
Applications
IHC,ELISA
-
Reactivity
Human
-
Dilution
IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
-
Storage
-20°C/1 year
-
Specificity
Phospho-ATR (S428) Polyclonal Antibody detects endogenous levels of ATR protein only when phosphorylated at S428.
-
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogen
The antiserum was produced against synthesized peptide derived from human ATR around the phosphorylation site of Ser428. AA range:394-443
-
Uniprot No
Q13535
-
Alternative names
ATR; FRP1; Serine/threonine-protein kinase ATR; Ataxia telangiectasia and Rad3-related protein; FRAP-related protein 1
-
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
Clonality
Polyclonal
-
Isotype
IgG
-
Background
ATR serine/threonine kinase(ATR) Homo sapiens The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008],
-
Other
ATR, Serine/threonine-protein kinase ATR
-
Mol.Wt (Da)
301367
-
Concentration
1 mg/ml
| Product | Reactivity | Applications | Conjugation | Catalog | Images |
|---|
采購中心
化工儀器網