化工儀器網(wǎng)>產(chǎn)品展廳>環(huán)境監(jiān)測(cè)儀器>其它環(huán)境監(jiān)測(cè)儀器>其它環(huán)境儀器> AVP Receptor V2 rabbit pAb2
AVP Receptor V2 rabbit pAb2
- 公司名稱 上海貝博生物科技有限公司
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- 廠商性質(zhì) 生產(chǎn)廠家
- 更新時(shí)間 2025/7/13 21:40:22
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Source
Rabbit
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Applications
WB,IF,ELISA
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Reactivity
Human
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Dilution
WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
AVP Receptor V2 Polyclonal Antibody detects endogenous levels of AVP Receptor V2 protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human AVPR2. AA range:72-121
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Uniprot No
P30518
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Alternative names
AVPR2; ADHR; DIR; DIR3; V2R; Vasopressin V2 receptor; V2R; AVPR V2; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptor
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
arginine vasopressin receptor 2(AVPR2) Homo sapiens This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus
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Other
AVPR2, Vasopressin V2 receptor; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptor
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Mol.Wt (Da)
40279
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Concentration
1 mg/ml
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