AXIN1 rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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Source
Rabbit
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Applications
WB,ELISA
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Reactivity
Human,Mouse,Rat
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Dilution
WB 1:500-2000 ELISA 1:5000-20000
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Storage
-20°C/1 year
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Specificity
AXIN1 Polyclonal Antibody detects endogenous levels of protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
Synthesized peptide derived from human protein . at AA range: 190-270
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Uniprot No
O15169
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Form
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
axin 1(AXIN1) Homo sapiens This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
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Other
AXIN1 AXIN, Axin-1 (Axis inhibition protein 1) (hAxin)
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Concentration
1 mg/ml
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