AVR2B rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 廠商性質(zhì) 生產(chǎn)廠家
- 更新時(shí)間 2025/7/13 21:19:30
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Source
Rabbit
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Applications
WB,ELISA
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Reactivity
Human,Mouse,Rat
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Dilution
WB 1:500-2000 ELISA 1:5000-20000
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Storage
-20°C/1 year
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Specificity
AVR2B Polyclonal Antibody detects endogenous levels of protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
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Uniprot No
Q13705
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Form
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
activin A receptor type 2B(ACVR2B) Homo sapiens Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligａnd binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. Th
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Other
ACVR2B, Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)
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Concentration
1 mg/ml
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