Bad (phospho Ser136) rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 廠商性質 生產廠家
- 更新時間 2025/7/13 20:03:42
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Source
Rabbit
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Applications
WB,IHC,ELISA
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Reactivity
Human,Mouse,Rat
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Dilution
WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
Phospho-Bad (S112) Polyclonal Antibody detects endogenous levels of Bad protein only when phosphorylated at S112.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human BAD around the phosphorylation site of Ser112. AA range:78-127
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Uniprot No
Q92934
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Alternative names
BAD; BBC6; BCL2L8; Bcl2 antagonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-XL/Bcl-2-associated death promoter
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
BCL2 associated agonist of cell death(BAD) Homo sapiens The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008],
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Other
BAD, Bcl2 antagonist of cell death; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-XL/Bcl-2-associated death promoter
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Mol.Wt (Da)
18392
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Concentration
1 mg/ml
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