Bak rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 廠商性質 生產廠家
- 更新時間 2025/7/13 19:29:48
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Source
Rabbit
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Applications
WB,IHC,IF,ELISA
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Reactivity
Human,Mouse
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Dilution
WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
Bak Polyclonal Antibody detects endogenous levels of Bak protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human Bak. AA range:1-50
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Uniprot No
Q16611
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Alternative names
BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
BCL2 antagonist/killer 1(BAK1) Homo sapiens The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008],
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Other
BAK1, Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7
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Mol.Wt (Da)
23409
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Concentration
1 mg/ml
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