4E-BP1 rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 更新時間 2025/7/12 17:36:50
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Source
Rabbit
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Applications
WB,IHC,ELISA
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Reactivity
Human,Mouse,Rat
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Dilution
WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
Phospho-4E-BP1 (S64) Polyclonal Antibody detects endogenous levels of 4E-BP1 protein only when phosphorylated at S64.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human 4E-BP1 around the phosphorylation site of Ser64. AA range:30-79
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Uniprot No
Q13541
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Alternative names
EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
eukaryotic translation initiation factor 4E binding protein 1(EIF4EBP1) Homo sapiens This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008],
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Other
EIF4EBP1, Eukaryotic translation initiation factor 4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1
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Mol.Wt (Da)
12449
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Concentration
1 mg/ml
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