CCDB1 rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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Source
Rabbit
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Applications
WB
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Reactivity
Human, Mouse,Rat
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Dilution
WB 1:500-2000
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Storage
-20°C/1 year
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Specificity
This antibody detects endogenous levels of CCDB1 at Human/Mouse/Rat
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Source/Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
Synthesized peptide derived from human CCDB1
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Uniprot No
O95273
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009],
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Other
CCNDBP1 DIP1 GCIP HHM, CCDB1
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Mol.Wt (Da)
39600
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Concentration
1 mg/ml
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