CD1B rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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Source
Rabbit
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Applications
IHC,ELISA
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Reactivity
Human
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Dilution
IHC 1:50-200, ELISA 1:10000-20000
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Storage
-20°C/1 year
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Specificity
The antibody detects endogenous CD1B
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
Synthetic peptide from human protein at AA range: 60-100
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Uniprot No
P29016
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Alternative names
T-cell surface glycoprotein CD1b (CD antigen CD1b)
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
CD1b molecule(CD1B) Homo sapiens This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008],
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Other
CD1B, T-cell surface glycoprotein CD1b (CD antigen CD1b)
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Concentration
1 mg/ml
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