BioFlex CellSoft培養板 基底膜剛度細胞牽張培育裝置系統
- 公司名稱 世聯博研(北京)科技有限公司
- 品牌 其他品牌
- 型號 BioFlex CellSoft培養板
- 產地 美國flexcell
- 廠商性質 代理商
- 更新時間 2020/2/26 11:33:43
- 訪問次數 1046
聯系方式:李勝亮13261877206 查看聯系方式
聯系我們時請說明是化工儀器網上看到的信息,謝謝!
應用領域 | 醫療衛生,生物產業 |
---|
基底膜剛度細胞牽張培育裝置系統,基底膜彈性可調細胞牽張拉伸動態培養或靜態培養(1-180kpa),適合原代和干細胞牽張拉伸培養,BioFlex CellSoft培養板是當今wei一可在商業上可行的可施加細胞拉伸負荷的柔軟表面。
美國Flexcell細胞應力加載培養與實時觀察分析系統,包括:
1.1.FX-5000T體外細胞拉應力加載培養與實時觀察分析系統
1.2.FX-5000C細胞組織壓應力加載培養與實時觀察分析系統
1.3.FX-5000TT細胞組織三維拉應力加載培養與實時觀察分析系統
1.4.STR-4000流體剪切應力加載培養與實時觀察分析系統。
其產品成熟度高、成功應用文獻量達4000多篇,國內有包括上海交通大學、復旦大學、同濟大學、上海第九醫院、中科院力學所、北京大學第三醫院、北航生物與醫學工程學院、都醫科大學、廣州醫科大學、南方科技大學、福建協和醫院、南方醫科大學近100家成功高校、醫院及基礎科研單位使用,無技術風險和使用風險,flexcell體外高通量細胞牽張拉伸力、壓應力以及流體剪切力加載培養系統已成為細胞力學體外加載模型的黃金標準,是細胞組織力學研究者的shou選。
CellSoft™ Soft Substrate References
Key References:
Buxboim et al., How deeply do cells feel:methods for thin gels. J Phys Condens matter. 22: 1-19, 2010.
Chodhury et al., Soft substrates promote homogeneous self-renewal of embryonic stem cells via down regulating cell-matrix tractions. PLOS 1 5: 1-10, 2010.
Engle et al., Matrix elasticity directs stem cell lineage specification. Cell 126: 677-689, 2006.
Hirata and Yamaoka. Effect of stem cell niche elasticity/ECM protein on the self-beating cardiomyocyte differentiation of iPS cells at different stages. Acta Biomat. 65: 44-52, 2018
Megone et al., Impact of surface adhesion and sample heterogeneity on the multiscale mechanical characterization of soft biomaterials. Sci Rep 8: 6780, 2018.
Ou et al., Visualizing mechanical modulation of nanoscale organization of cell-matrix adhesions. Integr. Biol. 8: 795-804,2016.
Palchesko et al., Development of polydimethylsiloxane substrates with tunable elastic modulus to study cell mechanobiology in muscle and nerve. PLOS 1 7: 1-13, 2012
Smith et al., Mechanosensing of matrix by stem cells: from matrix heterogeneity, contractility and the nucleus in pore-migration to cardiogenesis and muscle stem cells in vivo. Sem Cell Devtbio. 71: 84-98, 2017
Solon et al., Fibroblast adaptation andstiffness matching to soft elastic substrates. Biophys J. 93: 4453-4461, 2007.
Thomas et al., Measuring the mechanical properties of living cells using atomic force microscopy. J Visual Exp. 76:1-8, 2013.
Vertelov et al., Rigidity of silicone substrates controls cell spreading and stem cell differentiation. Sci Rep. 6:1-10, 2016.