seebio 三烯生育酚delta-Tocotrienol ——西寶生物專業供應
參考價 | ¥ 13 |
訂貨量 | ≥1 |
- 公司名稱 西寶生物科技(上海)股份有限公司
- 品牌
- 型號 seebio
- 產地 seebio
- 廠商性質 經銷商
- 更新時間 2016/10/19 13:53:28
- 訪問次數 192
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三烯生育酚delta-Tocotrienol ——西寶生物專業供應
Description Tocotrienols contain an arene ring, a chromanol ring, and an isoprenoid tail; all tocotrienol compounds contain a methyl group on C8 of the arene ring. δ-Tocotrienol contains only the methyl group at C8; all other available sites are substituted with hydrogen atoms. Tocotrienols are members of the vitamin E family, typically isolated from natural sources such as vegetable oils, nuts, and grains. Tocotrienols exhibit strong antioxidative activity as well as antiangiogenic, anticancer, and lipid-lowering qualities. Of all of the tocotrienols, δ-Tocotrienol displays the strongest antiangiogenic and anticancer activities. Tocopherols, common substituents of over-the-counter vitamin E supplements, interfere with tocotrienol activity and show weaker antioxidative effects. Tocotrienols exhibit significant radical recycling abilities in cellular models of lipid peroxidation and oxidative damage and suppress HMG-CoA reductase activity. In vitro, these compounds induce apoptosis through inhibition of Id1, EGFR, and NF-κB, and also inhibit vessel formation and proliferation in aortic endothelial cells.三烯生育酚delta-Tocotrienol ——西寶生物專業供應 | |
Specifications | |
Cas No.25612-59-3Product IDHT5611Product Name三烯生育酚 delta-TocotrienolSynonymδ-Tocotrienol, delta-TocotrienolFormula Wt.396.61Purity>98%Store Temp-20°CReferencesYap WN, Chang PN, Han HY, et al. Gamma-tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways. Br J Cancer. 2008 Dec 2;99(11):1832-41. PMID: 19002171. Sen CK, Khanna S, Roy S. Tocotrienols: Vitamin E beyond tocopherols. Life Sci. 2006 Mar 27;78(18):2088-98. PMID: 16458936. Inokuchi H, Hirokane H, Tsuzuki T, et al. Anti-angiogenic activity of tocotrienol. Biosci Biotechnol Biochem. 2003 Jul;67(7):1623-7. PMID: 12913317. Parker RA, Pearce BC, Clark RW, et al. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Biol Chem. 1993 May 25;268(15):11230-8. PMID: 8388388. Serbinova E, Kagan V, Han D, et al. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol. Free Radic Biol Med. 1991;10(5):263-75. PMID: 1649783三烯生育酚delta-Tocotrienol ——西寶生物專業供應 |